FullStack Java Developer
AstraZeneca Pharmaceuticals LP
Contract Wilmington, Delaware, United States Posted 3 months ago
About Position
FullStack Java Developer (Contract)
$85.00 / Hourly
Wilmington, Delaware, United States
FullStack Java Developer
Contract Wilmington, Delaware, United States Posted 3 months ago
Skills
Seeking candidates with over 3 years of experience in Agile development and full-stack service creation with a strong emphasis on frontend development. A solid background in scientific programming and collaboration with scientific experts particularly in the fields of Chemistry Physics or Cheminformatics is essential. The ideal candidate will have extensive experience in developing and deploying end-to-end solutions in a research or scientific environment. Development Services: Tech Stack Backend: *Java 11/17 *Maven *Junit – Mockito * Web services based on Springboot (Core MCV Security Rest Client\WebClient JPA(Hibernate)) Frontend: *ReactJS *Redux *MaterialUI *Jest *NPM CI/CD: *Jenkins for some apps with migration to GitHub actions (now integration with Sonar is done) Cloud: *AWSDescription
LCMS Analysis is used as standard method to determine the quality of synthesized Oligonucleotides, Peptides and their Conjugates. Due to the size and complexity of the molecules, the analysis is time consuming and today supported by large Excel Spreadsheets and personal experience of the Scientists which limits the results. In this project we plan to develop a webservice, which can predict and name structure sensitive impurities for Oligonucleotides, Peptides and their Conjugates. Properties of these impurities, like m/z values and charge states shall be calculated as well as possible MS adducts and fragments originating from the measurement technique. To support different workflows across PharmSci, the webservice shall allow for different output formats, as well as an API to allow automation. During the last year, a POC has been established which has some of the required functionality. It is expected from the developer to work closely with the Scientists to understand
Responsibilities
- • Webservice with UI for input of: AZ identifier, parameter control for the prediction and output/download of the result
- • Backend handling the impurity predictions
- • Management of impurities and impurity types
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